Related Experiment Video
Updated: Jan 26, 2026

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
RANDOMIZED PROSPECTIVE STUDY ON THE TREATMENT OF FEMORO-PATELLAR OSTEOARTHRITIS USING BRACING
Gustavo Jum Yamamoto1, Guilherme Pereira Ocampos1, Maria Candidade Miranda Luzo1
1Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Department of Orthopedics and Traumatology, São Paulo, Brazil.
Both a functional knee brace and a neoprene sleeve improved pain and function for patients with femoropatellar osteoarthritis. The functional brace offered pain relief without increasing naproxen use.
Area of Science:
- Orthopedics
- Biomechanical Engineering
Background:
- Patellofemoral osteoarthritis (OA) is a common condition causing pain and functional limitation.
- Various orthotic devices are used to manage symptoms, but their comparative efficacy requires further investigation.
Purpose of the Study:
- To compare the effectiveness of a functional knee brace designed for patellofemoral joint stabilization against a patella-shaped neoprene sleeve with a patella cutout in patients with patellofemoral OA.
Main Methods:
- Fifty-seven patients with patellofemoral OA were randomized into two groups: functional brace or neoprene sleeve.
- Both groups received standard clinical treatment and medication, with assessments at baseline, 1 month, and 3 months post-intervention.
- Outcome measures included WOMAC and Lequesne questionnaires, Five Times Sit to Stand test, Timed Up and Go test, and the Six-Minute Walk Test.
Main Results:
- Both orthoses led to significant improvements in pain, stiffness, and function, with no statistically significant differences between the groups.
- Medication use initially decreased but increased by the third month in both groups.
- Naproxen consumption was notably higher in the control (neoprene sleeve) group.
Conclusions:
- Both functional knee braces and neoprene sleeves are effective in improving pain and function in patients with patellofemoral OA.
- The functional knee brace provided comparable pain relief to the neoprene sleeve but without an increase in naproxen usage.
- Orthotic interventions can influence medication use patterns in the short term.
More Related Videos
06:28Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
09:01Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
Related Concept Videos
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
Random Error
Random Variables
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
Randomized Experiments
Simple randomization
Simple...
Random and Systematic Errors
Random Sampling Method