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Correlation Between Dysphagia and Malocclusion in Rett Syndrome: A preliminary study.

Serena Cocca1, Massimo Viviano2, Michele Loglisci1

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|April 17, 2019
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Summary

This study found that more severe malocclusion in patients with Rett syndrome (RS) is linked to increased dysphagia severity. Understanding this connection is crucial for managing digestive issues in RS patients.

Keywords:
DysphagiaFeeding and Eating Disorders of ChildhoodMalocclusionRett SyndromeX-Linked Mental Retardation

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Area of Science:

  • Neurology
  • Gastroenterology
  • Dental Medicine

Background:

  • Rett syndrome (RS) is a severe neurodevelopmental disorder.
  • Key features include hand stereotypies, seizures, craniofacial differences, and digestive problems.
  • Dysphagia and malocclusion are common in RS, but their relationship is not well-defined.

Purpose of the Study:

  • To investigate the correlation between malocclusion severity and dysphagia in Rett syndrome patients.
  • To provide insights into the oral and digestive health challenges faced by individuals with RS.

Main Methods:

  • A preliminary study involving 56 female patients with Rett syndrome.
  • Patients were assessed for dysphagia severity (absent to severe) and malocclusion.
  • Data collected from January 2014 to December 2017 at a university hospital.

Main Results:

  • A significant positive correlation was found between malocclusion severity and dysphagia.
  • Higher degrees of malocclusion were associated with increased severity of swallowing difficulties.
  • P <0.001 indicated a statistically significant relationship.

Conclusions:

  • Increased malocclusion severity is associated with more severe dysphagia in Rett syndrome.
  • This finding highlights the importance of dental and swallowing assessments in RS management.
  • Further research may explore interventions targeting these interconnected issues.