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Related Experiment Video

Updated: Jan 26, 2026

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
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[Intracranial hemorrhage masquerading as STEMI].

P Kreuzer1, G Hackl1, F Eisner1

  • 1Allgemeine Intensivstation, Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Auenbruggerplatz 15, 8036, Graz, Österreich.

Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|April 17, 2019
PubMed
Summary
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Electrocardiogram changes mimicking ST-elevation myocardial infarction (STEMI) can occur with intracranial hemorrhage. This case underscores the importance of considering non-cardiac causes for these critical findings.

Area of Science:

  • Neurology
  • Cardiology
  • Emergency Medicine

Background:

  • ST-elevation myocardial infarction (STEMI) is a critical cardiac emergency.
  • Intracranial hemorrhage can present with diverse neurological symptoms.
  • Electrocardiographic (ECG) changes are common in various medical conditions.

Observation:

  • A 56-year-old woman presented with unconsciousness and ECG findings suggestive of STEMI, including ST elevations in leads I, aVL, V1-V4.
  • Initial management included thrombolytic therapy based on ECG findings.
  • Subsequent investigations revealed massive intracranial hemorrhage on CT scan, with no surgical options, and elevated troponin T levels.

Findings:

  • Coronary angiography ruled out significant coronary artery disease as the cause of the ST elevations.
Keywords:
ComaLysisSTEMISubarachnoidal hemorrhageTako-tsubo

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  • The patient was diagnosed with massive intracranial hemorrhage.
  • Brain death was confirmed 54 hours after presentation.

    • Implications:

    • This case underscores the potential for intracranial hemorrhage to present with electrocardiographic changes that mimic acute myocardial infarction.
    • Clinicians must maintain a high index of suspicion for non-cardiac causes, particularly neurological emergencies, when interpreting ECG findings.
    • Accurate diagnosis is crucial to guide appropriate management and avoid potentially harmful interventions in cases of pseudo-STEMI due to ICH.