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Updated: Jan 26, 2026

In Vivo Assay for Detection of Antigen-specific T-cell Cytolytic Function Using a Vaccination Model
Published on: November 28, 2017
Antigen specific vaccine hesitancy in pregnancy
P G Van Buynder1, J L Van Buynder2, L Menton2
1School of Medicine, Griffith University, Southport, Queensland, Australia; Gold Coast Health Service, Southport, Queensland, Australia.
Maternal pertussis vaccination is successful, but influenza vaccine uptake in pregnancy remains low. Improving public and practitioner perception of influenza vaccine benefits is crucial for better maternal and infant health outcomes.
Area of Science:
- Public Health
- Immunization
- Maternal and Child Health
Background:
- Vaccinations during pregnancy protect newborns from pertussis and pregnant individuals from influenza.
- Published Australian data indicated suboptimal vaccination coverage rates in pregnant women.
Purpose of the Study:
- To investigate the reasons behind suboptimal vaccination coverage rates in pregnant women in Australia.
- To identify barriers to maternal pertussis and influenza vaccination.
Main Methods:
- A cross-sectional survey was conducted with 1014 postnatal women on the Gold Coast, Queensland, Australia.
- Participants completed questionnaires via smart tablets, phone, or online link.
Main Results:
- Over 85% of women received a pertussis booster; many who didn't had received it in a recent pregnancy.
- Only 36.7% received the influenza vaccine during pregnancy, citing vaccine beliefs, timing, and lack of provider recommendation as barriers.
Conclusions:
- Maternal pertussis vaccination programs are effective, but influenza vaccine uptake needs improvement.
- Enhancing public perception of influenza vaccine safety and efficacy, and addressing practitioner recommendations are essential for increasing coverage.
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