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Published on: March 17, 2023
Early Cognitive and Adaptive Functioning of Clinically Referred Infants and Toddlers with Cancer
Ansley E Kenney1, Jennifer L Harman1, Andrew E Molnar1
1Department of Psychology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 740, Memphis, TN, 38105, USA.
Insights
Infants and toddlers with cancer show significantly below-average developmental and adaptive functioning. Early cancer diagnosis in young children risks developmental delays, necessitating further research for optimal outcomes.
Area of Science:
- Pediatric Oncology
- Developmental Psychology
- Clinical Psychology
Background:
- Cancer diagnosis in infancy and toddlerhood (under 3 years) can disrupt crucial developmental periods.
- Young children with cancer face potential missed developmental opportunities.
- Early childhood cancer impacts cognitive and adaptive development.
Purpose of the Study:
- To describe the developmental and adaptive functioning of infants and toddlers with cancer.
- To evaluate children referred for psychological assessment at a hospital-based clinic.
- To identify risks for developmental weaknesses in very young children with cancer.
Main Methods:
- Retrospective data abstraction from 29 children diagnosed with cancer before age 3.
- Analysis of clinically referred assessments conducted between 2010 and 2015.
- Evaluation of developmental and adaptive functioning in infants and toddlers post-cancer diagnosis.
Main Results:
- Overall developmental functioning was significantly below expected levels (p < .001).
- Adaptive functioning was also significantly below expectations (p < .001).
- Children assessed were, on average, 23.62 months old and 11.3 months post-diagnosis.
Conclusions:
- Infants and toddlers with cancer are at significant risk for impaired cognitive and adaptive functioning.
- Deficits observed warrant further investigation into this population.
- Early intervention and support are crucial for optimizing functional development in young children with cancer.
Abstract:
Many children with cancer are diagnosed during infancy and toddlerhood (< 3 years of age), potentially resulting in disrupted and/or missed developmental opportunities. Our objective was to describe the functioning of infants and toddlers with cancer who were clinically referred for evaluation at a hospital-based psychology clinic. Data from 29 very young children with cancer (Mage = 23.62 ± 6.6 months; 55.2% male) who completed clinically referred assessments from 2010 to 2015 were abstracted. Children were 11.3 months post-diagnosis (SD = 7.77, range 1-29 months) with just over half off-therapy at the time of assessment (55.2%). Overall, developmental functioning was significantly below expectations [t(22) = - 8.99, p < .001]. Adaptive functioning [t(25) = - 6.41, p < .001] was also significantly below expectations. Infants and toddlers with cancer appear to be at significant risk for weaknesses in early cognitive and adaptive functioning. The margin of deficits found in this study warrant the need for further investigation and consideration of this young population to ensure optimal functional development.
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