Related Experiment Video

Updated: Jan 26, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

9.9K

[Analysis of flowmetric parameters of blood flow through coronary bypass grafts in high-risk surgical patients]

R V Sidorov1, E P Talalaev1, V N Shchetko1

  • 1Rostov State Medical University, Rostov-on-Don, Russia.

Angiologiia I Sosudistaia Khirurgiia = Angiology and Vascular Surgery
|April 18, 2019
PubMed

Insights

Coronary artery bypass grafting (CABG) on a beating heart or arrested heart showed comparable blood flow in grafts for high-risk patients. Beating heart surgery significantly reduced complication risks.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Anesthesia
  • Vascular Physiology

Background:

  • Coronary artery bypass grafting (CABG) is a common procedure for ischemic heart disease.
  • CABG can be performed on an arrested heart with cardiopulmonary bypass or on a beating heart without bypass.
  • Previous studies indicate no significant differences in outcomes between the two techniques.

Purpose of the Study:

  • To analyze flowmetric blood flow parameters in coronary bypass grafts.
  • To compare outcomes of CABG on arrested versus beating hearts in high-surgical risk patients.
  • To assess the impact of surgical technique on complication rates.

Main Methods:

  • A study of 148 high-surgical risk patients with ischemic heart disease undergoing CABG.
  • Patients were divided into two groups based on surgical technique: arrested heart (artificial circulation) or beating heart (no artificial circulation).
  • Flowmetric parameters of blood flow through coronary bypass grafts were analyzed.

Main Results:

  • Statistical data showed comparable results between the arrested heart and beating heart groups.
  • Operative interventions on the beating heart significantly decreased the risk of most complications.
  • No significant differences were observed in flowmetric parameters between the two groups.

Conclusions:

  • Both cardiopulmonary bypass and beating heart techniques yield comparable flowmetric results in coronary bypass grafts.
  • Beating heart surgery offers a significant advantage in reducing complication risks for high-risk patients undergoing CABG.
  • The choice of technique should consider the potential for decreased complication rates with beating heart procedures.

Keywords:
artificial circulationblood flow velocitycoronary artery bypass graftinghigh surgical riskischaemic heart diseaseultrasound flowmetry

More Related Videos

Author Spotlight: Enhancing Coronary Artery Revascularization05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

1.2K
Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model12:00

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Published on: November 24, 2014

15.9K

Related Concept Videos

Blood Flow01:29

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
75.7K
Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
7.6K
Noncompartmental Analysis: Miscellaneous Pharmacokinetic Parameters00:54

Noncompartmental Analysis: Miscellaneous Pharmacokinetic Parameters

The noncompartmental approach is a widely used method in pharmacokinetics to assess drugs' behaviors in the body. It considers several factors, including clearance, bioavailability, and total volume of distribution.
One key aspect of the noncompartmental approach is determining a drug's total clearance. This can be done by dividing the drug dose by the area under the concentration-time curve from zero to infinity. The area under the concentration-time curve represents the drug's...
441
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.0K
Wave Parameters01:10

Wave Parameters

The simplest mechanical waves are associated with simple harmonic motion and repeat themselves for several cycles. These simple harmonic waves can be modeled using a combination of sine and cosine functions. Consider a simplified surface water wave that moves across the water's surface. Unlike complex ocean waves, in surface water waves, water moves vertically, oscillating up and down, whereas the disturbance of the wave moves horizontally through the medium. If a seagull is floating on the...
9.1K
Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
7.0K