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Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery
Published on: March 4, 2021
Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical
Wan-Yin Fang1, L Ravindar1, K P Rakesh1
1School of Chemistry, Chemical Engineering and Life Science, School of Materials Science and Engineering, Wuhan University of Technology, 205 Luoshi Road, Wuhan, 430070, PR China.
Abstract:
At present more than 250 FDA approved chlorine containing drugs were available in the market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is quite obvious to expect that in coming decades there will be an even greater number of new chlorine-containing pharmaceuticals in market. Chlorinated compounds represent the family of compounds promising for use in medicinal chemistry. This review describes the recent advances in the synthesis of chlorine containing heterocyclic compounds as diverse biological agents and drugs in the pharmaceutical industries for the inspiration of the discovery and development of more potent and effective chlorinated drugs against numerous death-causing diseases.
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