Acute non-heparin-induced thrombocytopenia during hemodiafiltration in a patient with multiple myeloma

Makiko Morita1, Kayoko Nakanishi1, Kenta Masuda1

  • 1Department of Clinical Laboratory Kyoto University Hospital Kyoto Japan.

Clinical Case Reports
|April 19, 2019
PubMed

This report demonstrates that not only heparin-induced thrombocytopenia, but also hemodialysis conditions (platelet activation due to hemodiafiltration and heparin underdosing) may markedly reduce the platelet count and cause clotting in the hemodialysis circuit in patients in a hypercoagulable state. The clot prevention effects of bortezomib are therefore of great importance.

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