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Defining Frailty in Research Abstracts: A Systematic Review and Recommendations for Standardization.

E Yaksic1, V Lecky, S Sharnprapai

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This summary is machine-generated.

Frailty definitions are often incomplete in research abstracts. This study found only 16% of abstracts provided a complete frailty definition, hindering systematic reviews and meta-analyses.

Keywords:
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Area of Science:

  • Gerontology
  • Clinical Research Methodology
  • Epidemiology

Background:

  • Multiple definitions of frailty exist, leading to inconsistencies in research.
  • Inconsistent definitions complicate the synthesis of evidence through systematic reviews and meta-analyses.

Purpose of the Study:

  • To quantify the frequency of incomplete frailty definitions in published research abstracts.
  • To identify common frailty measures and assess the completeness of their definitions.

Main Methods:

  • Systematic review of MEDLINE/PubMed for English abstracts of original human research on frailty (2015-2017).
  • Defined a complete frailty definition by four criteria: named measure, included variables, number of variables, and cutoffs/levels.
  • Analyzed 490 abstracts that met review criteria, focusing on the 348 that provided any definition of frailty.

Main Results:

  • Only 56 out of 348 (16%) abstracts provided a complete definition of frailty.
  • 90% of abstracts reported a single frailty measure, with Fried's phenotype and Rockwood's cumulative deficit model being most common.
  • 35% of abstracts named a frailty measure but provided no further details.

Conclusions:

  • A minority of frailty research abstracts offer adequate definitions.
  • Incomplete definitions impede systematic reviews, meta-analyses, and accurate reporting in frailty science.
  • Standardized definition approaches in abstracts are encouraged to improve the quality of frailty research.