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Published on: December 16, 2015
Antibiotic Residues in Milk Supplies in Zimbabwe
Lameck S Chagonda1, Jason Ndikuwera1
1Department of Pharmacy and Department of Clinical Veterinary Studies, University of Zimbabwe, P.O. Box MP167, Mount Pleasant, Harare, Zimbabwe.
Abstract:
Raw milk samples from 73 individual milk producers were obtained at the three main Dairy Marketing Board (DMB) collection centers in Zimbabwe during the period of January to February, 1988. The samples were examined for the presence of antibiotics using the Delvotest-P (Gist-Brocades) ampoule test method with a sensitivity of 0.002 I.U. of penicillin per ml of milk. Four samples (5.5%) contained more than 0.005 I.U. of penicillin per ml or equivalent. Two (2.8%) samples contained antibiotics other than penicillin. An antibiotic depletion study using 23 cows treated with a multiple antibiotic intramammary infusion product, streptomycin - penicillin mixture (Dispolac RX4 B®; Coopers, South Africa), indicated a withholding period of 7-8 d was necessary to obtain milk free of detectable residues. The sensitivity of the Delvotest-P for streptomycin was determined by the manufacturers and found to be 4-6 μg/ml.
Insights
Antibiotic residues were detected in raw milk from Zimbabwe producers. A 7-8 day withdrawal period is recommended after intramammary infusion to ensure milk safety.
Area of Science:
- Veterinary Medicine
- Food Safety
- Microbiology
Background:
- Antibiotic residues in raw milk pose a significant food safety concern.
- Contamination can arise from therapeutic treatments in dairy herds.
- Monitoring antibiotic residues is crucial for public health and trade.
Purpose of the Study:
- To assess the prevalence of antibiotic residues in raw milk from Zimbabwean producers.
- To determine the necessary withholding period for specific antibiotic treatments to ensure milk is residue-free.
Main Methods:
- Collected 73 raw milk samples from three Dairy Marketing Board centers in Zimbabwe (Jan-Feb 1988).
- Utilized the Delvotest-P ampoule test to detect penicillin and other antibiotic residues.
- Conducted an antibiotic depletion study with 23 cows treated with a streptomycin-penicillin mixture.
Main Results:
- 5.5% of samples contained penicillin residues above the threshold (≥0.005 I.U./ml).
- 2.8% of samples showed residues of antibiotics other than penicillin.
- A withholding period of 7-8 days was required for the streptomycin-penicillin product to achieve residue-free milk.
Conclusions:
- Antibiotic residues are present in raw milk from Zimbabwe, necessitating improved management practices.
- A 7-8 day withholding period is crucial for intramammary antibiotic treatments to prevent residue contamination.
- Continued surveillance and adherence to withdrawal periods are essential for milk safety.
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