Related Experiment Video
Updated: Jan 26, 2026
07:39
Mouse In Vivo Placental Targeted CRISPR Manipulation
Published on: April 14, 2023
3.6K
CRISPR-Directed Microbiome Manipulation across the Food Supply Chain
Rodolphe Barrangou1, Richard A Notebaart2
1Genomic Sciences Program, NC State University, Raleigh, NC, USA; Department of Food, Bioprocessing and Nutrition Sciences, NC State University, Raleigh, NC, USA.
Trends in Microbiology
|April 21, 2019
Summary
CRISPR genome editing technologies can modify food bacteria to enhance food production and safety. These tools offer precise control over microbial communities throughout the food supply chain.
Area of Science:
- Genetics and Microbiology
- Food Science and Technology
Background:
- CRISPR technologies have revolutionized genetic applications in medicine and agriculture.
- Genome editing offers potential for controlling food bacteria and optimizing the food supply chain.
Purpose of the Study:
- To discuss CRISPR technologies for altering bacterial functionalities in food.
- To illustrate applications for modulating microbial communities in food.
Main Methods:
- Review of CRISPR-based technologies and their applications in food microbiology.
- Discussion of microbiome manipulation strategies in the food supply chain.
Main Results:
- CRISPR tools can alter bacterial functions and community composition in food.
- Applications span from farm to consumer products, impacting fermentation, quality, and safety.
Conclusions:
- CRISPR technologies provide powerful means to manage food microbiomes.
- These advancements can enhance food products and ensure safety by controlling spoilage and pathogenic bacteria.
Related Concept Videos
01:59CRISPR
57.6K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
57.6K
02:53CRISPR and crRNAs
18.9K
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
18.9K
01:28Electron Transport Chains
111.8K
The final stage of cellular respiration is oxidative phosphorylation that consists of two steps: the electron transport chain and chemiosmosis. The electron transport chain is a set of proteins found in the inner mitochondrial membrane in eukaryotic cells. Its primary function is to establish a proton gradient that can be used during chemiosmosis to produce ATP and generate electron carriers, such as NAD+ and FAD, that are used in glycolysis and the citric acid cycle.
The ETC is comprised of...
The ETC is comprised of...
111.8K
01:27Nerve Supply of the GI Tract
3.4K
The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of...
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of...
3.4K
01:16Blood Supply to the Digestive System
5.2K
Splanchnic circulation refers to the network of blood vessels that supply and drain blood from the abdominal organs involved in digestion, including the stomach, liver, pancreas, intestines, and spleen. This circulation delivers essential nutrients and oxygen while removing waste products from these organs.
Blood Supply to the Digestive System: The splanchnic circulation involves three main arteries: the celiac artery (also known as the celiac trunk) and the superior and inferior mesenteric...
Blood Supply to the Digestive System: The splanchnic circulation involves three main arteries: the celiac artery (also known as the celiac trunk) and the superior and inferior mesenteric...
5.2K
01:17Radical Chain-Growth Polymerization: Chain Branching
2.5K
The skeletal structure of polymers synthesized via radical polymerization is always branched. For example, the polymerization of ethylene by radical polymerization results in a low-density grade of polyethylene with a heavily branched skeletal structure. Here, the radical site abstracts hydrogen from the growing chain, and the radical site shifts from the end (a primary carbon center) to anywhere within the growing chain (a secondary carbon center). Consequently, the part of the chain from the...
2.5K