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Updated: Jan 26, 2026

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The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
Published on: February 7, 2025
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The predictive dysphagia score (PreDyScore) in the short- and medium-term post-stroke: a putative tool in PEG
Carlo Gandolfo1,2, Samir Sukkar3,
1Clinica Neurologica dell'Università di Genova, Genoa, Italy. gandcaci@unige.it.
Summary
Persistent dysphagia after stroke is predicted by low body mass index (BMI) and high modified Rankin Scale (mRS) scores. The developed PreDyScore accurately identifies patients at risk, aiding clinical management.
Area of Science:
- Neurology
- Gastroenterology
- Clinical Medicine
Background:
- Dysphagia is a common complication following stroke, impacting patient recovery and quality of life.
- Identifying early predictors of persistent dysphagia is crucial for timely intervention and management.
Purpose of the Study:
- To identify factors associated with persistent dysphagia one month after stroke.
- To develop a predictive score for persistent dysphagia in stroke patients.
Main Methods:
- A cohort of 249 stroke patients was evaluated for dysphagia at 7 and 30 days post-admission.
- Univariate and multivariate logistic regression analyses were used to identify predictive factors.
- A predictive score (PreDyScore) was formulated based on significant clinical variables.
Main Results:
- At 30 days, 36.76% of patients had persistent dysphagia.
- Factors significantly associated with dysphagia included age >74 years, TACI, mRS ≥3, malnutrition, and BMI ≥20.
- Multivariate analysis confirmed mRS ≥3 and BMI ≥20 as significant predictors. The PreDyScore demonstrated high sensitivity (67.03%) and specificity (95.65%).
Conclusions:
- Low body mass index (BMI <20) and high modified Rankin Scale (mRS ≥3) scores are easily measurable bedside predictors of persistent dysphagia.
- The PreDyScore is a reliable tool for predicting persistent dysphagia with high accuracy in clinical settings.
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