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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Investigation of smell and taste function in patients with obstructive sleep apnoea syndrome
A Yenigun1, N Degirmenci1, S S Goktas1
1Department of Otorhinolaryngology,Faculty of Medicine,Bezmialem Vakif University,Istanbul,Turkey.
Objective:
This study investigated the relationship between disease severity and taste and smell functions in patients with obstructive sleep apnoea syndrome.
Methods:
A total of 65 patients with recurrent upper airway obstruction during sleep were included. Participants were divided into four groups according to apnoea-hypopnoea index, obtained on polysomnography. Smell and taste tests were performed on these patients.
Results:
A significant difference was observed between the smell thresholds of the groups for the identification test (p = 0.016). In the taste test, significant differences were observed between the groups in terms of sweet, sour, salty and bitter taste test thresholds (p = 0.029, p = 0.0005, p = 0.001 and p = 0.017, respectively).
Conclusion:
As sleep apnoea severity increased (according to the apnoea-hypopnoea index) in obstructive sleep apnoea syndrome patients, the taste and smell thresholds decreased due to the effect of neuropathy and inflammation in the upper respiratory tract.
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