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Updated: Dec 25, 2025

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
Published on: September 22, 2023
Red-green-blue analysis of nasal mucosa discolouration in allergic rhinitis
N Degirmenci1, R Dogan1, S Tugrul1
1Department of Otorhinolaryngology, Bezmialem Vakif University, Istanbul, Turkey.
Objective:
To evaluate the colour values of nasal mucosa for the purpose of presenting an objective parameter of allergic rhinitis.
Methods:
Seventy-three patients with allergic rhinitis (allergy group) and 73 normal healthy individuals (control group) were included in the study. Endoscopic examinations were conducted, and endoscopic photographs of the septum and both inferior turbinates were taken. The Adobe Photoshop Elements 7.0 software program was used to measure the numerical values of red-green-blue (RGB) colour components in the endoscopic photographs of nasal mucosa.
Results:
The G and B values were significantly higher in the allergy group compared to the control group (both p < 0.05). Cumulative R, G and B values of all measurement points were significantly higher in the allergy group compared to the control group (p < 0.05).
Conclusion:
Nasal mucosa discolouration can be measured objectively with RGB analysis to aid the diagnosis of allergic rhinitis.
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