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Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
Alexandra M Danakas1, Bushra G Fazili2,3, Aaron R Huber1
1Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 626, Rochester, NY 14642, USA.
Case Reports in Pathology
|April 23, 2019
Summary
Ischemic colitis, a condition from reduced blood flow to the colon, can rarely present as a mass. Prompt diagnosis of this ischemic colitis variant prevents misdiagnosis and unnecessary surgery.
Area of Science:
- Gastroenterology
- Pathology
- Vascular Medicine
Background:
- Ischemic colitis (IC) arises from diminished colonic vascular perfusion, representing a significant portion of gastrointestinal ischemic events.
- The severity of IC correlates with the extent and duration of colonic injury, potentially causing mucosal damage.
- Rarely, IC can manifest as a mass-like lesion, closely resembling gastrointestinal malignancy.
Observation:
- A 55-year-old female presented with hematochezia and diarrhea.
- Diagnostic workup revealed a mass-like lesion at the ileocecal valve.
- Biopsies confirmed ischemic changes and mucosal injury, excluding dysplasia or carcinoma.
Findings:
- Histopathological examination showed ischemic colitis with mucosal injury.
- No evidence of dysplasia or malignancy was found in the biopsies.
- Follow-up imaging two months later demonstrated complete resolution of the lesion after supportive treatment.
Implications:
- Awareness of this IC variant is crucial for gastroenterologists and pathologists.
- Recognizing IC as a cause of mass-like lesions can prevent misdiagnosis.
- Appropriate identification avoids unnecessary surgical interventions and treatments for patients.
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