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Cardiovascular Drugs: Classification based on Therapeutic Indications

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Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...

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Related Experiment Video

Updated: Jan 26, 2026

Wet-spinning-based Molding Process of Gelatin for Tissue Regeneration

Wet-spinning-based Molding Process of Gelatin for Tissue Regeneration

Published on: March 7, 2019

Recent advances in gelatin-based therapeutics.

Mari Carmen Echave^1,2, Raquel Hernáez-Moya^1,2, Leire Iturriaga^1,2

¹a NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy , University of the Basque Country UPV/EHU, Paseo de la Universidad 7 , Vitoria-Gasteiz , Spain.

Expert Opinion on Biological Therapy

|April 23, 2019

Summary

Gelatin, a natural biopolymer, offers versatile applications in regenerative medicine, including drug delivery and tissue engineering. Recent advancements enhance its use in biomaterial development for various therapeutic strategies.

Keywords:

Biomaterial drug delivery gelatin regenerative medicine tissue engineering

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Published on: December 21, 2019

Area of Science:

Biomaterials Science
Regenerative Medicine
Polymer Chemistry

Background:

Gelatin, derived from collagen, is a natural biopolymer extensively utilized in regenerative medicine.
Its cell-responsive properties and biomolecule delivery capacity make it valuable.
Gelatin's applications span drug delivery, tissue engineering, 3D/4D Bioprinting, and organ-on-a-chip platforms.

Purpose of the Study:

To present the properties and therapeutic applications of gelatin as a biomaterial.
To highlight recent advances in gelatin-based biomaterials for drug delivery and tissue engineering.
To discuss current challenges and limitations in gelatin-based approaches.

Main Methods:

Review of gelatin's properties and applications in regenerative medicine.
Analysis of recent advancements in polymer chemistry, mechanobiology, imaging, and 3D biofabrication.
Identification of challenges and limitations in current gelatin-based research.

Main Results:

Gelatin exhibits significant potential in various biomedical applications, including bone and cartilage tissue engineering, wound healing, and anti-cancer therapy.
Technological advancements have broadened the scope of gelatin's utility in drug delivery and tissue engineering.
Key challenges and limitations in current gelatin-based strategies are identified.

Conclusions:

Gelatin is a promising biomaterial for tissue engineering and regenerative medicine.
Continued research and technological innovation are crucial for overcoming limitations and expanding gelatin's therapeutic applications.
Gelatin-based biomaterials hold significant potential for future biomedical breakthroughs.