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Published on: July 14, 2023
Serological survey for antibodies to Encephalitozoon cuniculi in cats within the United States
C Kourgelis1, C Reilly2, M Von Roedern3
1Division of Comparative Pathology, Department of Pathology & Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL 33101, USA.
Abstract:
Encephalitozoon cuniculi is an obligate intracellular microsporidian parasite that causes clinical and subclinical infection in many species. It is also considered a potential zoonotic disease. In the present study, a serological survey was conducted using samples from pet cats using an ELISA with a confirmed positive control sample from a cat with E. cuniculi related uveitis. Thirty-four of 127 serum samples or 26.8% were found to demonstrate reactivity with titers ranging from 1:32 to 1:1024. There were no significant differences by age or sex (p=0.99 and p=0.32, respectively). This is the first description of the use of an enzyme linked immunosorbent assay for the detection of E. cuniculi antibodies in cats in the United States.
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