Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Periodic Table03:25

The Periodic Table

109.9K
As early chemists discovered more elements, they realized that various elements could be grouped by their similar chemical behaviors. One such grouping includes lithium (Li), sodium (Na), and potassium (K). All of these elements are shiny, conduct heat and electricity well, and have similar chemical properties. A second grouping includes calcium (Ca), strontium (Sr), and barium (Ba), which also are shiny, good conductors of heat and electricity, and have chemical properties in common. However,...
109.9K
Periodic Classification of the Elements04:00

Periodic Classification of the Elements

58.8K
The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...
58.8K
Autonomic Nervous System01:22

Autonomic Nervous System

12.4K
The autonomic nervous system (ANS) is a critical component of the peripheral nervous system, primarily responsible for regulating involuntary bodily functions and maintaining homeostasis. It functions in tandem with the central nervous system (CNS) to seamlessly coordinate various physiological processes without the need for conscious control.
The ANS comprises two main divisions: the sympathetic and parasympathetic divisions. These divisions function antagonistically to maintain a dynamic...
12.4K
Effective Value of a Periodic Waveform01:07

Effective Value of a Periodic Waveform

1.2K
The concept of effective value, the root mean square (RMS) value, is crucial in understanding electrical circuits and power delivery. This idea emerges from the necessity to measure the effectiveness of a voltage or current source in supplying power to a resistive load.
The effective value of a periodic current represents the direct current (DC) that conveys the same average power to a resistor as the periodic current itself. This concept is crucial when assessing AC circuits. To determine the...
1.2K
The Periodic Table and Organismal Elements00:57

The Periodic Table and Organismal Elements

201.1K
Overview
201.1K
The Periodic Table and Organismal Elements01:27

The Periodic Table and Organismal Elements

22.3K
Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
22.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Method to fabricate round cross-sectional channel using thermal expansion of air for passive flow regulators.

Electrophoresis·2023
Same author

Hydraulic-electric analogy for design and operation of microfluidic systems.

Lab on a chip·2023
Same author

Cascaded microfluidic circuits for pulsatile filtration of extracellular vesicles from whole blood for early cancer diagnosis.

Science advances·2023
Same author

Mechanical Timer-Actuated Fluidic Dispensing System: Applications to an Automated Multistep Lateral Flow Immunoassay with High Sensitivity.

Analytical chemistry·2022
Same author

Size-selective filtration of extracellular vesicles with a movable-layer device.

Lab on a chip·2022
Same author

Influence of surface tension-driven network parameters on backflow strength.

RSC advances·2022
Same journal

Erratum for the Research Article "Assessing the health risks of rice cadmium content standards in China" by H. Chu <i>et al</i>.

Science advances·2026
Same journal

Erratum for the Research Article "Developmental regulation of Erk signaling by mitotic kinases" by F. Chen <i>et al</i>.

Science advances·2026
Same journal

Magnetically levitated metasurface enabling tangible and bidirectional human-machine interaction.

Science advances·2026
Same journal

A general photoinduced manganese-catalyzed platform for the sequential difunctionalization of [1.1.1]propellane.

Science advances·2026
Same journal

Turning sound and force into light with AlN:Mn<sup>2+</sup> mechanoluminescence.

Science advances·2026
Same journal

Extreme dominance of Earth-origin heavy ions in the intense ring current near the Earth during the May 2024 super geomagnetic storm.

Science advances·2026
See all related articles

Related Experiment Video

Updated: Jan 25, 2026

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators
12:04

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators

Published on: May 20, 2018

9.4K

Autonomous microfluidic actuators for periodic sequential flow generation.

Zhenglin Li1, Sung-Jin Kim1

  • 1Department of Mechanical Engineering, Konkuk University, Seoul 05029, Republic of Korea.

Science Advances
|April 25, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces novel microfluidic systems that autonomously control periodic sequential flows, eliminating the need for complex external controllers. These systems offer a simpler, effective alternative for various scientific and technological applications.

More Related Videos

A Versatile Kit Based on Digital Microfluidics Droplet Actuation for Science Education
05:46

A Versatile Kit Based on Digital Microfluidics Droplet Actuation for Science Education

Published on: April 26, 2021

5.2K
Free-form Light Actuators &#8212; Fabrication and Control of Actuation in Microscopic Scale
08:17

Free-form Light Actuators — Fabrication and Control of Actuation in Microscopic Scale

Published on: May 25, 2016

9.6K

Related Experiment Videos

Last Updated: Jan 25, 2026

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators
12:04

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators

Published on: May 20, 2018

9.4K
A Versatile Kit Based on Digital Microfluidics Droplet Actuation for Science Education
05:46

A Versatile Kit Based on Digital Microfluidics Droplet Actuation for Science Education

Published on: April 26, 2021

5.2K
Free-form Light Actuators &#8212; Fabrication and Control of Actuation in Microscopic Scale
08:17

Free-form Light Actuators — Fabrication and Control of Actuation in Microscopic Scale

Published on: May 25, 2016

9.6K

Area of Science:

  • Microfluidics
  • Analog Electronics
  • Fluid Dynamics

Background:

  • Controlling periodic sequential flows of multiple solutions is crucial for many applications but typically requires complex and costly external controllers.
  • Existing methods for precise flow control are often cumbersome and expensive, limiting their widespread adoption.
  • There is a need for autonomous, cost-effective systems capable of managing intricate fluidic sequences.

Purpose of the Study:

  • To develop autonomous microfluidic systems for regulating periodic sequential flows without external controllers.
  • To demonstrate that these microfluidic systems can mimic the functionality of analog electronic circuits for flow control.
  • To validate the system's efficacy in applications previously requiring dynamic external controllers.

Main Methods:

  • Design and fabrication of microfluidic devices incorporating astable and monostable actuators.
  • Utilizing a constant water head pressure as the sole driving force for fluid manipulation.
  • Integration of actuator designs to autonomously generate predetermined periodic sequential flows.
  • Testing the system's performance in dynamic cell nucleus staining and a touchscreen piano application.

Main Results:

  • The developed microfluidic systems autonomously generated precise periodic sequential flows without user intervention or external control.
  • The systems successfully mimicked the logic functions of analog electronic circuits using microfluidic components.
  • Demonstrated successful application in dynamic cell nucleus staining and a touchscreen piano, matching performance of systems with external controllers.
  • The sole driving force of constant water head pressure was sufficient for sophisticated flow regulation.

Conclusions:

  • Microfluidic systems with astable and monostable actuators offer an autonomous solution for controlling periodic sequential flows.
  • This technology provides a cost-effective and simpler alternative to traditional dynamic external controllers.
  • The demonstrated applications highlight the versatility and practical utility of these self-regulating microfluidic devices.