Related Experiment Video
Updated: Jan 25, 2026

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
Published on: December 5, 2016
Detection of N6‑methyladenosine modification residues (Review)
Wei Zhu1, Jing-Zi Wang2, Zhiqiang Xu1
1Research Division of Clinical Pharmacology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210000, P.R. China.
Abstract:
Among a number of mRNA modifications, N6‑methyladenosine (m6A) modification is the most common type in eukaryotes and nuclear‑replicating viruses. m6A has a significant role in numerous cancer types, including leukemia, brain tumors, liver cancer, breast cancer and lung cancer. Although m6A methyltransferases are essential during RNA modifications, the biological functions of m6A and the underlying mechanisms remain to be fully elucidated, predominantly due to the limited detection methods for m6A. In the present review, the currently available m6A detection methods and the respective scope of their applications are presented to facilitate the further investigation of the roles of m6A in biological process.
Related Concept Videos
Residual Stresses
Residual Plots
When the residual values are plotted against the variable x, it is called a residual...
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Histone Modification
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
Residual Stresses in Circular Shafts

