Related Experiment Video
Updated: Jan 25, 2026

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
Published on: June 14, 2017
Ruptured mitral valve abscess with mitral incompetence in culture negative infective endocarditis: case report
Raja Dashti1, Mohammed Al Jarallah1, Rajesh Rajan1
1Department of Cardiology, Sabah Al Ahmad Cardiac Center, Al-Amiri Hospital, Bin Misbah Street, Capital Governorate , Sharq, Kuwait City, 15300 Kuwait.
Introduction:
Perivalvular abscess in native valve infective endocarditis (IE) is associated with significantly increased mortality.
Case Description:
Herein, we report a 29 year old Indian male who presented with culture negative IE with perivalvular abscess and severe mitral regurgitation requiring mitral valve replacement.
Discussion:
Initial approach is very difficult in terms of when IE presents as culture negative. This case highlights the important role of echocardiography in the management of culture negative IE.
Insights
Perivalvular abscess in native valve infective endocarditis (IE) increases mortality. Echocardiography is crucial for managing culture-negative IE, as demonstrated in a case of severe mitral regurgitation.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Perivalvular abscess in native valve infective endocarditis (IE) is linked to higher mortality rates.
- Culture-negative IE presents diagnostic challenges.
Observation:
- A 29-year-old Indian male presented with culture-negative IE and a perivalvular abscess.
- The patient had severe mitral regurgitation necessitating mitral valve replacement.
Findings:
- Echocardiography played a vital role in diagnosing and managing this complex case.
- The study underscores the utility of echocardiography in culture-negative IE.
Implications:
- Early and accurate diagnosis of IE, even when cultures are negative, is critical for patient outcomes.
- This case emphasizes the importance of advanced imaging in guiding treatment for severe IE complications.
More Related Videos
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Valve Prolapse III: Nursing Management
Mitral Regurgitation I: Introduction
Mitral Stenosis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis

