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Updated: Jan 25, 2026

Genome-wide Analysis of Aminoacylation Charging Levels of tRNA Using Microarrays
Published on: June 18, 2010
tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences
Patricia P Chan1, Todd M Lowe2
1Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.
Abstract:
Transfer RNAs are the largest, most complex non-coding RNA family, universal to all living organisms. tRNAscan-SE has been the de facto tool for predicting tRNA genes in whole genomes. The newly developed version 2.0 has incorporated advanced methodologies with improved probabilistic search software and a suite of new gene models, enabling better functional classification of predicted genes. This chapter describes the use of the UNIX command-driven and online web versions, illustrating different search modes and options.
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