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Bioinspired Smart Nanosystems in Advanced Therapeutic Applications
Satya Prakash Singh1, Anup Kumar Sirbaiya1, Anuradha Mishra1
1Department of Pharmaceutics, Faculty of Pharmacy, Integral University, Lucknow-226026, U.P, India.
Pharmaceutical Nanotechnology
|April 26, 2019
Summary
Bioinspired smart nanocarriers offer targeted drug delivery for various disorders. This review examines challenges in developing these biocompatible nanomaterials for enhanced therapeutic applications.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Drug Delivery Systems
Background:
- Nanoparticle technologies for human administration require interaction with the host environment.
- Bioinspired smart drug delivery carriers utilize biocompatible nanomaterials for targeted drug delivery.
- These systems aim to improve therapeutic efficacy and reduce side effects.
Purpose of the Study:
- To review the challenges in developing bioinspired smart nanocarriers.
- To explore their applications in targeted drug delivery.
- To understand their potential in managing various disorders.
Main Methods:
- Literature review of bioinspired smart nanosystems.
- Analysis of nanomaterial composition (lipids, polymers, biomaterials).
- Examination of responsive sensors and external stimuli affecting nanosystems.
Main Results:
- Bioinspired nanocarriers can deliver drugs, diagnostics, and genetic material to target sites.
- Nanosystems are composed of lipids, polymers, and biomaterials with responsive sensors.
- External factors like temperature, pH, and electromagnetic fields impact nanosystem performance.
Conclusions:
- Development of bioinspired smart nanocarriers faces significant challenges.
- Overcoming these challenges is crucial for effective management of various disorders.
- Further research is needed to optimize these advanced drug delivery systems.
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