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Age-dependent reference values of the thyroid gland in pediatric population; from routine computed tomography data

Jin Hee Sea1, Hye Ji1, Sun Kyoung You2

  • 1Department of Radiology, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Republic of Korea.

Clinical Imaging
|April 27, 2019
PubMed

Insights

Thyroid gland size increases with age in children. Right lobe depth is a reliable indicator of total thyroid volume in pediatric patients, aiding in clinical assessments.

Area of Science:

  • Radiology
  • Pediatric Endocrinology
  • Anatomy

Background:

  • Accurate thyroid gland measurements are crucial for pediatric health assessments.
  • Establishing age-dependent reference values is essential for diagnosing thyroid abnormalities in children.

Purpose of the Study:

  • To determine age-specific reference values for thyroid gland dimensions in pediatric patients.
  • To investigate the correlation between thyroid gland measurements and patient age.

Main Methods:

  • Retrospective review of 425 pediatric computed tomography scans.
  • Measurement of thyroid gland dimensions (width, depth, length) and total volume.
  • Comparison of measurements across six age groups (0–18 years).

Main Results:

  • Significant positive linear correlations were found between age and all thyroid measurements (r = 0.58–0.82).
  • Total thyroid volume strongly correlated with linear lobe measurements (r > 0.7).
  • Right lobe depth demonstrated the highest correlation with total thyroid volume (r = 0.859).

Conclusions:

  • Thyroid gland volume in children increases with age.
  • Right lobe depth can serve as a key indicator for estimating total thyroid gland volume in pediatric populations.
  • These findings align with previous adult studies, suggesting a consistent anatomical relationship.
Abstract

Keywords:
AdolescentsChildrenComputed tomographyReference valuesThyroid gland

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