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See, Think, and Act: Real-Time Adaptive Radiotherapy
Paul Keall1, Per Poulsen2, Jeremy T Booth3
1ACRF Image X Institute, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Seminars in Radiation Oncology
|April 28, 2019
Summary
Real-time adaptive radiotherapy uses a continuous see, think, and act loop for smarter cancer treatment. This approach leverages real-time data and imaging for optimized, adaptive radiotherapy delivery.
Area of Science:
- Oncology
- Medical Physics
- Radiotherapy Technology
Background:
- The information age provides real-time data for decision-making.
- Cancer radiotherapy is advancing towards real-time adaptive radiotherapy.
- Driverless vehicle technology principles can inform radiotherapy advancements.
Purpose of the Study:
- To detail the three critical steps of real-time adaptive radiotherapy: see, think, and act.
- To provide historical context for adaptive radiotherapy.
- To review the clinical rationale and future outlook for real-time adaptive radiotherapy.
Main Methods:
- Utilizing imaging systems to monitor patient anatomy and physiology over time ('See').
- Employing current and prior data to optimize treatment with available adaptive parameters ('Think').
- Delivering the treatment in real-time based on adaptations ('Act').
Main Results:
- The paper outlines a framework for real-time adaptive radiotherapy.
- It details the 'see, think, act' loop analogous to driverless vehicles.
- The clinical rationale and historical context are presented.
Conclusions:
- Real-time adaptive radiotherapy represents a significant advancement in cancer treatment.
- The 'see, think, act' paradigm offers a structured approach to adaptive radiotherapy.
- Further development is expected to enhance treatment efficacy and patient outcomes.
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