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Extraction: Effects of pH00:53

Extraction: Effects of pH

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Consider a neutral form of an amine, B, with a partition coefficient, K, in a liquid mixture containing organic and aqueous phases. The pH of the aqueous phase affects the charge on acidic and basic solutes, and the charged form is usually more soluble in the aqueous phase. Suppose the conjugate acid form of the amine is soluble only in the aqueous phase while the base form is soluble in both phases. Then the distribution coefficient, D, can be given as the ratio of amine concentration in the...
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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

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The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
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DNA Isolation01:34

DNA Isolation

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DNA from cells is required for many biotechnology and research applications, such as molecular cloning. To remove and purify DNA from cells, researchers use various methods of DNA extraction. While the specifics of different protocols may vary, some general concepts underlie the process of DNA extraction.
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What is Glycolysis?00:56

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Overview
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Hindsight bias leads you to believe that the event you just experienced was predictable, even though it really wasn’t. In other words, you knew all along that things would turn out the way they did. Can you relate this to the phrase "Hindsight is 20/20" now? 
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Updated: Jan 25, 2026

Ye's Swing Technique for Small-incision Lenticule Extraction Surgery
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Ye's Swing Technique for Small-incision Lenticule Extraction Surgery

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Hyperopic small-incision lenticule extraction.

Majid Moshirfar1,2,3, Cameron D Bruner4, David F Skanchy5

  • 1Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City.

Current Opinion in Ophthalmology
|April 30, 2019
PubMed
Summary
This summary is machine-generated.

Small-incision lenticule extraction (SMILE) is a promising surgical option for hyperopia correction, offering outcomes comparable to hyperopic laser-assisted in situ keratomileusis (LASIK). Advanced techniques like lenticule implantation may treat severe hyperopia in more patients.

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Area of Science:

  • Ophthalmology
  • Refractive Surgery

Background:

  • Small-incision lenticule extraction (SMILE) is established for myopia correction.
  • Limited data exists on SMILE for hyperopic eye disease.

Purpose of the Study:

  • To review recent advancements in SMILE for hyperopia.
  • To detail the outcomes of SMILE in treating hyperopic eye disease.

Main Methods:

  • Literature review of recent studies on SMILE for hyperopia.
  • Analysis of visual outcomes, safety, and healing profiles.

Main Results:

  • SMILE shows comparable visual outcomes, regression rates, safety, and wound healing to hyperopic LASIK.
  • Lenticule preservation and implantation show potential for higher hyperopia correction.

Conclusions:

  • SMILE is a viable alternative to LASIK for hyperopia correction.
  • Lenticule intrastromal keratoplasty techniques may address severe hyperopia in non-traditional candidates.