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Published on: September 19, 2019
Association between child psychiatric emergency room outcomes and dimensions of psychopathology
Thomas H McCoy1, Anna K Wiste2, Alysa E Doyle3
1Center for Quantitative Health, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02114, USA; Department of Psychiatry, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Insights
Dimensional psychopathology in children presenting to the emergency department (ED) impacts care duration. Symptoms of arousal and cognitive function significantly predict longer ED stays and hospital admission likelihood.
Area of Science:
- Child and Adolescent Psychiatry
- Emergency Medicine
- Computational Psychiatry
Background:
- Emergency departments (EDs) frequently manage children with psychiatric complaints.
- Predicting ED length of stay and admission is crucial for resource allocation and patient care.
- Dimensional approaches to psychopathology offer a nuanced understanding beyond diagnostic categories.
Purpose of the Study:
- To assess if dimensional psychopathology predicts ED length of stay and hospital admission in pediatric psychiatric patients.
- To explore the utility of the Research Domain Criteria (RDoC) framework in this clinical setting.
Main Methods:
- Analysis of electronic health records for 3061 children (aged 4-17) evaluated by psychiatry.
- Utilized natural language processing to estimate RDoC symptom domain scores.
- Regression models evaluated associations between RDoC scores, length of stay, and admission probability.
Main Results:
- Higher RDoC arousal, cognitive, positive, and social domain scores correlated with increased ED length of stay.
- Increased RDoC arousal and cognitive scores raised the odds of hospital admission.
- Higher RDoC negative domain scores decreased the odds of hospital admission.
Conclusions:
- Natural language processing-based RDoC scores effectively identify children at higher risk for prolonged ED stays and admission.
- This in silico approach supports precision psychiatry for pediatric emergency care.
- Arousal and cognitive symptom dimensions are key predictors of ED outcomes in children.
Objective:
To determine the degree to which dimensional psychopathology predicts length of stay in an emergency department (ED) and need for hospital admission among children with psychiatric complaints.
Method:
Electronic health records of children age 4-17 years who presented to the ED of a large academic medical center were analyzed using a natural language processing tool to estimate Research Domain Criteria (RDoC) symptom scores. These scores' association with length of stay and probability of admission versus discharge to home were evaluated.
Results:
We identified 3061 children and adolescents who presented to the ED and were evaluated by the psychiatry service between November 2008 and March 2015. Median length of stay was 7.8 h (interquartile range 5.2-14.3 h) and 1696 (55.4%) were admitted to the hospital. Higher estimated RDoC arousal, cognitive, positive, and social domain scores were associated with increased length of stay in multiple regression models, adjusted for age, sex, race, private insurance, voluntary admission, and diagnostic categories. In similarly adjusted models, odds of hospital admission were increased by higher RDoC arousal and cognitive domain scores and decreased by higher negative domain scores.
Conclusions:
A natural language processing tool to characterize dimensional psychopathology identified features associated with differential outcomes in children in the psychiatric ED, most notably symptoms reflecting arousal and cognitive function. Methodologically, this in silico approach to risk stratification should facilitate precision psychiatry in children within the emergency setting.
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