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Related Concept Videos

Lytic Cycle of Bacteriophages01:30

Lytic Cycle of Bacteriophages

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Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the...
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Lysogenic Cycle of Bacteriophages00:43

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In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
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DNA Bacteriophages01:26

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Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
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Types of Genetic Transfer Between Organisms02:18

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Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
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Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
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Plant Tissue Culture02:57

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Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
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Genetic Manipulation of the Plant Pathogen Ustilago maydis to Study Fungal Biology and Plant Microbe Interactions
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From Bacteriophage to Plant Genetics.

Barbara Hohn1

  • 1Friedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland;

Annual Review of Plant Biology
|May 1, 2019
PubMed
Summary

This scientist reflects on a career journey from bacteriophages to plant genomics, highlighting key research milestones and personal growth. The narrative emphasizes the collaborative and adventurous aspects of scientific exploration.

Keywords:
autobiographybacteriophage lambdaenvironmental impacthomologous recombinationplant DNA stabilityplant transformation

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Area of Science:

  • Molecular Biology
  • Plant Science
  • Genomics

Background:

  • Personal reflection on a scientific career.
  • Initial reluctance to write an autobiography.
  • Encouragement from peers to share life experiences.

Purpose of the Study:

  • To document a scientific journey and personal reflections.
  • To explore the evolution of research interests.
  • To share insights gained from a career in science.

Main Methods:

  • Autobiographical narrative.
  • Reflection on scientific career progression.
  • Chronological account of research evolution.

Main Results:

  • Traces research path from bacteriophages to Agrobacterium tumefaciens-mediated DNA transfer in plants, and finally to plant genomics.
  • Details personal and professional development from student to research leader.
  • Highlights significant scientific achievements and global exploration.

Conclusions:

  • Scientific careers are rich with milestones and personal growth.
  • The journey of a scientist involves continuous learning and adaptation.
  • Collaboration and exploration are vital components of scientific discovery.