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Sensitivities of Pityrosporum sp. to selected commercial shampoos

W Butterfield, M M Roberts, V K Dave

    The British Journal of Dermatology
    |February 1, 1987
    PubMed

    Insights

    This study evaluated Pityrosporum yeast sensitivity to four shampoos. Selsun and Cetavlon demonstrated potent fungicidal activity, proving most effective against these common yeast strains.

    Area of Science:

    • Dermatology
    • Mycology
    • Cosmetic Science

    Background:

    • Pityrosporum species are associated with various skin conditions.
    • Antifungal shampoos are commonly used to manage Pityrosporum-related issues.
    • Understanding shampoo efficacy against Pityrosporum is crucial for dermatological treatment.

    Purpose of the Study:

    • To assess the sensitivity of Pityrosporum yeast strains to four commercial shampoos.
    • To compare the fungistatic and fungicidal properties of different shampoo formulations.

    Main Methods:

    • Utilized a gel diffusion method to evaluate inhibition zones.
    • Determined minimum inhibitory concentrations (MICs) for each shampoo against Pityrosporum strains.
    • Tested 25 strains of Pityrosporum yeast.

    Main Results:

    • Undiluted shampoos showed inhibition zones against 13 of 15 tested Pityrosporum strains.
    • Two strains exhibited resistance to 'Polytar'.
    • 'Polytar' displayed fungistatic properties, while 'Selsun', 'Cetavlon P.C.', and 'Genisol' were fungicidal. 'Cetavlon' and 'Selsun' showed the lowest MICs.

    Conclusions:

    • Commercial shampoos vary in their efficacy against Pityrosporum yeast.
    • 'Selsun' and 'Cetavlon P.C.' exhibit strong fungicidal activity and are most effective.
    • Further research can guide the selection of appropriate antifungal shampoos for dermatological conditions.

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