Related Experiment Video

Updated: Jan 25, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
08:51

A New Murine Model of Endovascular Aortic Aneurysm Repair

Published on: July 7, 2013

14.8K

[Aortic aneurysms - epidemiology and therapeutic options]

Edin Mujagic1, Lorenz Gürke1

  • 11 Gefässchirurgie Universitätsspital Basel, Basel.

Therapeutische Umschau. Revue Therapeutique
|May 1, 2019
PubMed

Insights

Aortic aneurysms are more common in older men and share risk factors with atherosclerosis. Treatment choices balance rupture risk against procedural risk, with endovascular repair offering lower initial mortality but similar long-term outcomes to open repair.

Area of Science:

  • Vascular Surgery
  • Cardiovascular Epidemiology
  • Atherosclerotic Disease Research

Background:

  • Aortic aneurysms can affect any segment of the aorta.
  • Prevalence increases with age, predominantly affecting men over 65.
  • Risk factors are consistent with general atherosclerotic disease.

Purpose of the Study:

  • To review the epidemiology of aortic aneurysms.
  • To discuss current therapeutic options and their indications.
  • To compare outcomes of different treatment modalities.

Main Methods:

  • Review of epidemiological data on aortic aneurysm prevalence and risk factors.
  • Analysis of treatment indications based on aneurysm diameter and rupture risk.
  • Comparison of perioperative and long-term mortality rates for endovascular versus open repair.

Main Results:

  • Treatment for aortic aneurysms is invariably invasive.
  • Indications for intervention are determined by rupture risk (linked to maximum diameter) and treatment risks.
  • Endovascular repair shows lower perioperative mortality than open repair, but long-term mortality rates are comparable.

Conclusions:

  • Aortic aneurysm management requires careful consideration of patient-specific risks.
  • While endovascular repair offers early survival benefits, long-term surveillance is crucial for both methods.
  • Further research may elucidate long-term differences between endovascular and open aortic aneurysm repair.

More Related Videos

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model05:14

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

Published on: November 18, 2022

4.4K
Porcine Model of Infrarenal Abdominal Aortic Aneurysm11:13

Porcine Model of Infrarenal Abdominal Aortic Aneurysm

Published on: November 21, 2019

9.8K

Related Concept Videos

Introduction to Epidemiology01:26

Introduction to Epidemiology

Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.8K
Causality in Epidemiology01:21

Causality in Epidemiology

Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.5K
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
933
Confounding in Epidemiological Studies01:27

Confounding in Epidemiological Studies

Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
629
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
1.3K
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
396