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Updated: Jan 25, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

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[Venous thromboembolism - update 2019]

Sebastian Werth1

  • 11 Universitäts GefässCentrum - Universitätsklinikum Carl Gustav Carus Dresden.

Therapeutische Umschau. Revue Therapeutique
|May 1, 2019
PubMed

Insights

New diagnostic tools simplify venous thromboembolism (VTE) exclusion. New oral anticoagulants (NOACs) offer safer, simpler treatment and prophylaxis, reducing bleeding risk and VTE recurrence.

Area of Science:

  • Cardiology
  • Hematology
  • Internal Medicine

Background:

  • Venous thromboembolism (VTE) diagnosis and management have evolved.
  • New diagnostic algorithms and risk stratification tools are impacting clinical practice.

Purpose of the Study:

  • To provide an update on venous thromboembolism management in 2019.
  • To highlight the role of new diagnostic strategies and oral anticoagulants.

Main Methods:

  • Review of current diagnostic algorithms for VTE exclusion.
  • Application of risk scores for patient stratification.
  • Evaluation of new oral anticoagulants (NOACs) in treatment and prophylaxis.

Main Results:

  • Diagnostic certainty for VTE exclusion is improved, even for general practitioners.
  • Risk scores aid in identifying high-risk patients for monitoring.
  • Outpatient treatment for low-risk pulmonary embolism is increasingly feasible.
  • NOACs simplify treatment, reduce major bleeding compared to vitamin K antagonists, and show promise for paraneoplastic VTEs.
  • Prophylactic NOACs are expected to increase extended secondary prophylaxis, lowering recurrence risk.

Conclusions:

  • Modern diagnostic approaches enhance VTE exclusion certainty.
  • NOACs represent a significant advancement in VTE treatment and prophylaxis, offering improved safety and efficacy.
  • Future research should further validate NOACs for specific VTE types, such as paraneoplastic VTEs.

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