Related Experiment Video
Updated: Jan 25, 2026

Cutaneous Surgical Denervation: A Method for Testing the Requirement for Nerves in Mouse Models of Skin Disease
Published on: June 26, 2016
Abstract:
Cutaneous Rosai-Dorfman disease (CRDD) is a rare form of Rosai-Dorfman disease (RDD)(also known as sinus histiocytosis with massive lymphadenopathy) that has a varied clinical presentation, an unknown etiology, and multiple treatment options that lack efficacy. We present a case of a 31-year-old woman who presented with grouped flesh-colored to light pink papules and plaques within a hyperpigmented patch on the thigh that were treated with topical, oral, and intralesional steroids with minimal improvement.
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