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[Diphtheria, an imported disease].

T Krech, P Naumann, C Wittelsbürger

Deutsche Medizinische Wochenschrift (1946)

|April 3, 1987

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Diphtheria in Germany is primarily caused by imported strains from developing countries. However, systematic revaccination, even for adults, can prevent severe cases and fatalities.

Area of Science:

Epidemiology
Infectious Diseases
Public Health

Background:

Diphtheria remains a concern, particularly due to imported cases.
Understanding the origin of diphtheria strains is crucial for public health interventions.

Purpose of the Study:

To analyze the origins of diphtheria cases in the Federal Republic of Germany (FRG).
To assess the effectiveness of vaccination strategies in preventing severe diphtheria outcomes.

Main Methods:

Comparative analysis of 4256 residents and 4751 asylum applicants in the FRG.
Review of diphtheria case data from 1975 onwards.

Main Results:

Diphtheria in the FRG is predominantly caused by imported toxinogenic strains, mainly from developing countries.

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Between 1975 and the study period, 109 cases were recorded, with 22 deaths.

Severe outcomes were observed in the studied population.

Conclusions:

Imported diphtheria strains pose a significant public health risk in the FRG.
Systematic revaccination programs, including for adults, are effective in preventing severe diphtheria and mortality.