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Updated: Jan 25, 2026
07:01
Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
10.6K
Exaggerated Interventricular Dependence among Trauma and Burn Patients: A Relationship with Kidney Function-An
The American Surgeon
|May 3, 2019
Summary
Right ventricle shape, measured by left ventricular eccentricity index (LVEI), may predict acute kidney injury (AKI) risk in critically ill trauma and burn patients. Higher LVEI was linked to a lower incidence of AKI.
Area of Science:
- Critical Care Medicine
- Nephrology
- Cardiology
Background:
- Acute kidney injury (AKI) is a significant complication in critically ill patients, particularly those in the intensive care unit (ICU).
- Identifying predictive markers for AKI is crucial for timely intervention and improved patient outcomes.
Purpose of the Study:
- To investigate the association between right ventricle shape, assessed by left ventricular eccentricity index (LVEI), and the incidence of AKI.
- To explore LVEI as a potential surrogate marker for right ventricular volume loading in trauma and burn patients.
Main Methods:
- Retrospective review of 132 trauma and burn patients admitted to the ICU between 2013 and 2016.
- Hemodynamic transesophageal echocardiography was performed, with LVEI measurements from transgastric short-axis view clips at end diastole.
- Logistic regression analysis was used, adjusting for age, race, gender, injury mechanism, and injury severity.
Main Results:
- A higher LVEI was independently and significantly associated with a lower incidence of AKI.
- The adjusted odds ratio for AKI with higher LVEI was 0.03 (confidence interval 0.00-0.69).
- This suggests a protective association between specific right ventricle shapes and AKI development.
Conclusions:
- Right ventricle shape, indicated by LVEI, is associated with a reduced incidence of AKI in critically injured trauma and burn patients.
- LVEI may serve as a valuable indicator for predicting AKI risk in this vulnerable patient population.
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