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Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
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Subthreshold depression and its association with cardiovascular risk

Muhammad N Iqbal1, Fatima Iqbal

  • 1New York State Psychiatric Institute, Columbia University, New York, NY 10032 USA.

Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists
|May 3, 2019
PubMed

Insights

Subthreshold depression (SubD) significantly impacts cardiovascular disease (CVD) patients. Early identification and treatment of SubD are crucial for improving patient outcomes and quality of life in those with heart conditions.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Cardiovascular disease (CVD) is a leading global cause of death and morbidity.
  • Co-occurring CVD and major depressive disorder increase mortality and healthcare costs.
  • Subthreshold depression (SubD) shares characteristics with major depressive disorder and affects patient health.

Purpose of the Study:

  • To assess the prevalence of SubD in patients with CVD.
  • To examine the risk association between SubD and CVD.
  • To highlight the clinical significance of SubD in cardiovascular health.

Main Methods:

  • Systematic literature review of Medline and PubMed databases.
  • Inclusion of 11 high-quality studies from over 30 initially identified articles.
  • Focus on prevalence and risk association between SubD and CVD.

Main Results:

  • Subthreshold depression (SubD) is a significant factor impacting cardiovascular disease (CVD) patients.
  • SubD negatively affects the quality of life and overall health of individuals with CVD.

Conclusions:

  • Subthreshold depression (SubD) should be recognized as a distinct depressive disorder variant.
  • Healthcare providers require training to identify and manage SubD in CVD patients.
  • Pharmacologic and non-pharmacologic interventions are essential for treating SubD in this population.
Abstract

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