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Automated parenteral chemotherapy dose-banding to improve patient safety and decrease drug costs.
Olivia G Fahey1, Sara M Koth2, Jason J Bergsbaken1
1Department of Pharmacy, UW Health, Madison, WI, USA.
Summary
Automated parenteral chemotherapy dose-banding in electronic health records improved patient safety and reduced drug waste. This system standardization decreased medication errors and saved significant pharmacist time and costs.
Area of Science:
- Oncology
- Health Informatics
- Pharmacoeconomics
Background:
- Manual chemotherapy dosing can lead to variability and waste.
- Electronic health record (EHR) integration offers potential for process optimization.
Purpose of the Study:
- To enhance patient safety and minimize drug waste.
- To implement automated parenteral chemotherapy dose-banding within an EHR system.
Main Methods:
- Transitioned from manual to automated dose-rounding in the EHR.
- Developed dose-banding tables within a 10% parameter for bevacizumab, rituximab, and trastuzumab.
- Conducted a retrospective chart review to assess cost savings and safety improvements.
Main Results:
- Reduced medication errors related to chemotherapy rounding.
- Decreased event submissions from four to zero post-implementation.
- Saved pharmacists significant clicks and keystrokes, alongside notable drug cost savings.
Conclusions:
- Automated dose-banding improved the safety of parenteral chemotherapy ordering.
- Standardization of doses increased total drug and cost savings for key chemotherapy agents.
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