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The Hennepin Ketamine Study Investigators' Reply.

Jeffrey D Ho1, Jon B Cole1, Lauren R Klein1

  • 11.Hennepin Healthcare System, Department of Emergency Medicine, Minneapolis, Minnesota,USA.

Prehospital and Disaster Medicine
|May 4, 2019
PubMed
Summary

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This study addresses inaccuracies in commentary on the Hennepin Ketamine Study. It emphasizes the necessity of prehospital research in emergency medical services (EMS) despite consent challenges.

Area of Science:

  • Emergency Medicine
  • Prehospital Care Research
  • Clinical Research Ethics

Background:

  • Prospective clinical research in prehospital settings is crucial for advancing Emergency Medical Services (EMS) and emergency medicine.
  • Conducting such research presents challenges, particularly with patients unable to provide informed consent due to emergent conditions.
  • This reply addresses inaccuracies in an editorial and media reports concerning the Hennepin Ketamine Study.

Discussion:

  • The authors, as investigators of the Hennepin Ketamine Study, aim to clarify facts and address concerns raised by Dr. Samuel Stratton's editorial.
  • The editorial commented on research ethics, methodology, and public controversy surrounding the study.
  • The authors highlight the importance of accurate information for future prehospital research planning.
Keywords:
AMSS Altered Mental Status ScaleED emergency departmentEFIC Exception from Informed ConsentEMS Emergency Medical ServicesFDA Food and Drug AdministrationIND Investigational New DrugIRB Institutional Review BoardLAR legally authorized representativeWIC Waiver of Informed ConsentHennepinketamineresearchsedation

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Key Insights:

  • Prospective prehospital research is vital but ethically complex.
  • Inaccuracies in reporting can hinder scientific understanding and future studies.
  • Clarification of the Hennepin Ketamine Study details is necessary for the research community.

Outlook:

  • Encouraging accurate reporting and ethical considerations in prehospital research.
  • Facilitating future prospective clinical studies in emergency medical services.
  • Ensuring robust methodology and ethical conduct in emergency medicine research.