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The Experience of the Derivo® Embolisation Device in Intracranial Aneurysms

Ergun Daglioglu1, Ilkay Akmangit, Vedat Acik

  • 1Ankara Numune Training and Research Hospital, Department of Neurosurgery, Ankara, Turkey.

Turkish Neurosurgery
|May 4, 2019
PubMed

Insights

The Derivo® embolisation device (DED) safely and effectively treats brain aneurysms, showing good long-term outcomes. This new flow diverter achieved high occlusion rates with low complication risks in patients, including those with subarachnoid hemorrhage.

Area of Science:

  • Neurosurgery
  • Interventional Neuroradiology
  • Biomedical Engineering

Background:

  • Cerebrovascular aneurysms pose significant risks, including subarachnoid hemorrhage.
  • Flow diverters represent a new-generation treatment for complex aneurysms.
  • The Derivo® embolisation device (DED) is a novel flow diverter for aneurysm treatment.

Purpose of the Study:

  • To evaluate the safety and efficacy of the DED for treating cerebrovascular aneurysms.
  • To assess the long-term clinical outcomes of DED treatment.
  • To determine the occlusion rates and complication profile of DED.

Main Methods:

  • 146 patients with 182 aneurysms were treated using the DED.
  • The study included patients with acute subarachnoid hemorrhage and various aneurysm locations.
  • Aneurysm occlusion was assessed at a mean follow-up of 7.02 months.

Main Results:

  • The DED demonstrated a complete aneurysm occlusion rate of 78.7%.
  • The device was associated with a low mortality rate of 2.7% and permanent morbidity of 3.4%.
  • Favorable outcomes were observed even in patients presenting with subarachnoid hemorrhage.

Conclusions:

  • The DED is a safe and effective new-generation flow diverter for cerebrovascular aneurysms.
  • The device offers excellent opening and navigational properties.
  • DED treatment resulted in optimal morbidity and mortality rates, supporting its use in complex cases.
Abstract

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