Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO)...

Area of Science:

• Cardiology
• Nephrology
• Clinical Medicine

Background:

• Rising incidence and prevalence of heart failure (HF) and chronic kidney disease (CKD) globally.
• The critical need for improved understanding of the HF-CKD interface for effective management.
• Growing burden of cardiorenal comorbidities necessitates specialized guidelines.

Purpose of the Study:

• To summarize deliberations from the KDIGO Controversies Conference on Heart Failure in CKD.
• To address key questions regarding the detection, prevention, diagnosis, and management of HF in CKD patients.
• To provide insights into specific HF and CKD patient subgroups, including dialysis and transplant populations.

Main Methods:

• International, multidisciplinary expert consensus conference.
• Breakout group discussions focused on specific HF and CKD patient phenotypes.
• Review and synthesis of current evidence and clinical challenges in HF and CKD.

Main Results:

• Discussions covered HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF) in nondialysis CKD.
• Analysis included HF management in dialysis-dependent CKD and kidney transplant recipients.
• Identified knowledge gaps and areas for future research in cardiorenal medicine.

Conclusions:

• Optimal strategies for HF detection, prevention, diagnosis, and management in CKD require further research and consensus.
• The complex interplay between HF and CKD necessitates tailored approaches based on CKD stage and HF phenotype.
• International collaboration is crucial for advancing care for patients with cardiorenal conditions.