Severe Obesity in the Pediatric Population: Current Concepts in Clinical Care
Claudia K Fox1, Amy C Gross2, Eric M Bomberg2
1Center for Pediatric Obesity Medicine, Department of Pediatrics, University of Minnesota, 2450 Riverside Avenue, 6th floor, East Bldg, Minneapolis, MN, 55454, USA. Lusc0001@umn.edu.
Insights
Severe pediatric obesity requires comprehensive management. While lifestyle changes alone are insufficient, surgery is not scalable, highlighting the need for new pharmacotherapies and chronic care models.
Area of Science:
- Pediatric Endocrinology
- Obesity Medicine
- Public Health
Background:
- Severe obesity in children presents complex challenges.
- Contributing factors include biological, psychological, and social elements.
- Effective management strategies are critical for long-term health outcomes.
Purpose of the Study:
- To review the clinical assessment of pediatric severe obesity.
- To summarize contributing factors to severe obesity in youth.
- To evaluate current and emerging treatment strategies for pediatric severe obesity.
Main Methods:
- Comprehensive literature review of clinical assessment and treatment modalities.
- Analysis of biological, psychological, and social factors.
- Evaluation of lifestyle modification, pharmacotherapy, and bariatric surgery.
Main Results:
- Lifestyle modification alone is often insufficient for significant BMI reduction in severe pediatric obesity.
- Metabolic and bariatric surgery is effective but not a scalable solution.
- Emerging pharmacological agents show promise for addressing treatment gaps.
Conclusions:
- Severe pediatric obesity necessitates a chronic care management approach.
- Multidisciplinary teams and multi-pronged therapies are essential.
- Future treatments may involve a combination of pharmacotherapy and intensive management.
Purpose Of Review:
This review describes (1) the clinical assessment of pediatric patients with severe obesity, including a summary of salient biological, psychological, and social factors that may be contributing to the patient's obesity and (2) the current state of treatment strategies for pediatric severe obesity, including lifestyle modification therapy, pharmacotherapy, and metabolic and bariatric surgery.
Recent Findings:
Lifestyle modification therapy alone is insufficient for achieving clinically significant BMI reduction for most youth with severe obesity and metabolic and bariatric surgery, though effective and durable, is not a scalable treatment strategy. Pharmacological agents in the pipeline may 1 day fill this gap in treatment. Treatment of severe pediatric obesity requires a chronic care management approach utilizing multidisciplinary teams of health care providers and multi-pronged therapies.
Related Concept Videos
Self-Concept
Infancy and Emerging Recognition
During infancy, self-concept is virtually nonexistent. Babies do not distinguish themselves as separate entities and often mistake their...
Obesity
Concepts and Prototypes
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...
Formula Mass and Mole Concepts of Compounds
Conservation of Small Populations
What is Population Genetics?


