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CKD Hotspots: Challenges and Areas of Opportunity

Gregorio T Obrador1, Adeera Levin2

  • 1Department of Medicine, Universidad Panamericana School of Medicine, Mexico City, Mexico.

Seminars in Nephrology
|May 6, 2019
PubMed

Insights

Chronic kidney disease (CKD) is rising globally due to traditional factors and infections in specific "CKD hotspots." Addressing knowledge gaps and increasing research funding are crucial for prevention and treatment.

Area of Science:

  • Nephrology
  • Epidemiology
  • Global Health

Background:

  • Global burden of chronic kidney disease (CKD) is increasing.
  • CKD prevalence is rising due to diabetes, hypertension, and infections in specific geographic locations (CKD hotspots).
  • CKD of unknown etiology (CKDu) presents a significant public health challenge.

Purpose of the Study:

  • Summarize gaps and opportunities concerning CKD hotspots and CKDu.
  • Identify key areas for research, prevention, and treatment strategies.
  • Inform future research and clinical care initiatives.

Main Methods:

  • Discussion and synthesis of findings from a CKD Global Summit.
  • Analysis of existing knowledge gaps and areas for future development.
  • Expert consensus on challenges and opportunities in CKD hotspots.

Main Results:

  • Lack of universally accepted definitions for CKD hotspots and CKDu hinders understanding.
  • Limited knowledge exists regarding the causes of CKDu.
  • Insufficient resources and advocacy impede research and clinical care for CKD.
  • Opportunities lie in improved epidemiologic characterization, etiological research, prevention, treatment, funding, and education.

Conclusions:

  • Standardized definitions and etiological research are essential for CKD hotspots and CKDu.
  • Increased funding, advocacy, and education are critical for advancing CKD care globally.
  • Multifaceted strategies are needed to combat the rising burden of CKD.

Keywords:
Chronic kidney disease (CKD)challengeshotspotsresearch

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