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Association between Ménière's disease and vestibular migraine
Ilmari Pyykkö1, Vinaya Manchaiah2, Markus Färkkilä3
1Department of Otolaryngology, Hearing and Balance Research Unit, University of Tampere, Tampere, Finland. Electronic address: http://ilmari.pyykkotuni.fi.
Auris, Nasus, Larynx
|May 6, 2019
Summary
Ménière
Area of Science:
- Neurology
- Otolaryngology
Background:
- Ménière's disease (MD) and Vestibular Migraine (VM) are common vestibular disorders.
- The relationship and potential shared etiology between MD and VM remain incompletely understood.
Purpose of the Study:
- To investigate the association between MD and migraine/headache.
- To explore if MD and VM represent a disease continuum with shared pathophysiological mechanisms.
Main Methods:
- Retrospective study of 911 patients with MD from the Finnish Ménière Federation database.
- Analysis of questionnaire data using Mann-Whitney U, Kruskal Wallis H, logistic regression, and decision tree analyses.
Main Results:
- 20.9% of MD patients reported migraine, and 42.9% reported headache.
- Patients with VM experienced more severe MD symptoms, reduced quality of life, increased anxiety, and more neurological complaints compared to MD patients without migraine.
- Statistical analyses could not reliably differentiate VM from MD patients.
Conclusions:
- MD is frequently associated with headache and migraine.
- Migraine appears to exacerbate MD symptom severity.
- MD and VM may share underlying pathophysiological mechanisms, suggesting a need for a 'MD with migraine' classification.