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Allergic Reactions02:06

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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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PULMONARY DISEASE DIAGNOSTIC AND REHABILITATION TREATMENT FOR PATIENTS WITH OVERLAP ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASES.

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego·2023
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Related Experiment Video

Updated: Jan 25, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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Allergic rhinitis and asthma co-morbidity.

Victoria S Sukhan1

  • 1Uzhhorod National University, Uzhhorod, Ukraine.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|May 6, 2019
PubMed
Summary

Patients with allergic asthma and allergic rhinitis exhibit distinct phenotypes. This co-morbidity worsens asthma control, characterized by early allergy onset, family history, and elevated IgE and eosinophils.

Area of Science:

  • Immunology
  • Pulmonology
  • Genetics

Background:

  • Asthma and allergic rhinitis frequently co-occur, complicating disease management.
  • Understanding the specific features of this co-morbidity is crucial for effective treatment.

Purpose of the Study:

  • To analyze the genotypic and phenotypic characteristics of patients with co-existing asthma and allergic rhinitis.

Main Methods:

  • A study involving 115 patients divided into two groups: allergic asthma with allergic rhinitis (n=58) and non-allergic asthma (n=57).
  • Examination focused on identifying distinct features of asthma and allergic rhinitis in each group.

Main Results:

  • Patients with allergic asthma and allergic rhinitis often have a history of early-onset allergies (e.g., hay fever, atopic dermatitis) and a strong family history of allergies.
Keywords:
allergic rhinitisasthmaco-morbidity

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  • This co-morbidity is associated with aggravated asthma symptoms, distal airway obstruction, bronchial hyperresponsiveness, elevated IgE, eosinophilia, histamine, and exhaled nitric oxide (NO2).
  • Asthma control was significantly poorer in patients with co-existing allergic rhinitis compared to those with isolated asthma.

    • Conclusions:

    • The study successfully identified a distinct phenotype for patients experiencing co-morbid asthma and allergic rhinitis.
    • These findings aid in differentiating patients and potentially tailoring treatment strategies for this specific patient group.