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Updated: Jan 25, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Motor reaction time and accuracy in patients with multiple sclerosis: effects of an active computerized training
Amir Dana1, Saleh Rafiee2, Amin Gholami2
1Department of Physical Education, Tabriz Branch, Islamic Azad University, Tabriz, Iran. amirdana@iaut.ac.ir.
Cognitive-motor training significantly improved reaction time and accuracy in multiple sclerosis (MS) patients. This training enhanced information processing speed and precision compared to a control group.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
Background:
- Multiple sclerosis (MS) often impairs motor function and information processing.
- Quantifying these deficits is crucial for effective rehabilitation.
Purpose of the Study:
- To compare motor reaction time and accuracy between MS patients and healthy individuals.
- To evaluate the efficacy of a cognitive-motor training program in improving these parameters in MS patients.
Main Methods:
- 205 MS patients and 276 healthy subjects were assessed.
- MS patients were randomized into an active information processing training (AIPT) group or a control group.
- Simple, choice, and semantic reaction times and accuracies were measured before and after the intervention using the VLS battery.
Main Results:
- Significant differences in motor reaction times and accuracies were observed between MS patients and controls.
- Both AIPT and control groups showed improvements post-intervention.
- The AIPT group demonstrated significantly better performance in simple and choice motor reaction times compared to the control group.
Conclusions:
- Cognitive-motor training positively impacts motor reaction time and accuracy in MS patients.
- The findings support the use of targeted training to enhance information processing in MS.
- This study highlights the potential for rehabilitation strategies to mitigate MS-related motor deficits.
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