Purtscher-Like Retinopathy Associated with Synthetic Cannabinoid (Bonzai) Use

Area of Science:

• Ophthalmology
• Toxicology

Background:

• Purtscher’s retinopathy is a rare microvascular occlusive disease typically associated with trauma.
• Purtscher-like retinopathy presents similarly but is linked to systemic conditions.
• Synthetic cannabinoids, like Bonzai, are increasingly associated with adverse health effects.

Purpose of the Study:

• To describe the first documented case of Purtscher-like retinopathy associated with synthetic cannabinoid (Bonzai) use.
• To highlight a novel potential etiology for Purtscher-like retinopathy.

Main Methods:

• Ophthalmic examination including fluorescein angiography and optical coherence tomography.
• Clinical correlation of symptoms with substance use history.

Main Results:

• The patient presented with blurred vision and bilateral cotton-wool spots.
• Diagnostic imaging confirmed findings consistent with Purtscher-like retinopathy.
• The condition was directly linked to recent Bonzai use.

Conclusions:

• Synthetic cannabinoid (Bonzai) use can induce Purtscher-like retinopathy.
• This case expands the known causes of Purtscher-like retinopathy.
• Ophthalmologists should consider substance abuse in the differential diagnosis for patients presenting with Purtscher-like retinopathy.