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Symptomatic Vaginal Infection by Neisseria meningitidis Resulting in Meningitis with Septic Shock

Ryan Offman1,2, Elissa Boggs1,2, Adam Gwizdala2,3

  • 1Mercy Health-Muskegon, Department of Emergency Medicine, Muskegon, Michigan.

Clinical Practice and Cases in Emergency Medicine
|May 8, 2019
PubMed

Insights

Neisseria meningitidis can cause vaginitis, leading to severe meningitis. Early detection and aggressive treatment of vaginal N. meningitidis infections are crucial to prevent serious outcomes.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Obstetrics & Gynecology

Background:

  • Vaginitis is commonly caused by bacterial vaginosis, candidiasis, and trichomoniasis.
  • Symptomatic Neisseria meningitidis vaginitis is rare but associated with severe systemic disease.

Observation:

  • A case report details a patient with fulminant meningitis.
  • The meningitis was secondary to symptomatic vaginitis.
  • N. meningitidis was identified in vaginal cultures.

Findings:

  • This case highlights a rare but severe presentation of N. meningitidis vaginitis.
  • The infection progressed to meningitis, demonstrating the organism's potential for systemic spread.
  • Vaginal N. meningitidis infection carries a significant risk of morbidity and mortality.

Implications:

  • Physicians should be aware of N. meningitidis as a potential cause of vaginitis.
  • Prompt and aggressive treatment is recommended for patients with positive vaginal cultures for N. meningitidis.
  • Early recognition may prevent severe systemic complications like meningitis.

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