Related Experiment Video
Updated: Aug 30, 2025

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Exertional Near-Syncope: Pericardial Cyst as a Cause of Left Ventricular Outflow Obstruction
1Michigan State University College of Osteopathic Medicine, Mercy Health - Muskegon, Department of Emergency Medicine, Muskegon, Michigan.
Insights
A large pericardial cyst caused outflow obstruction in a healthy male, leading to near-syncope. Surgical resection resolved symptoms, highlighting cyst resection for symptomatic cases.
Area of Science:
- Cardiology
- Thoracic Surgery
- Medical Diagnostics
Background:
- Pericardial cysts are typically benign, fluid-filled sacs within the pericardium.
- While often asymptomatic, large pericardial cysts can cause significant cardiac complications.
- Left ventricular outflow obstruction is a rare but serious presentation of pericardial cysts.
Purpose of the Study:
- To report a case of symptomatic left ventricular outflow obstruction caused by a large pericardial cyst.
- To illustrate the diagnostic and therapeutic approach for such a condition.
- To emphasize the potential for pericardial cysts to cause hemodynamic compromise.
Main Methods:
- A 41-year-old male presented with recurrent exertional near-syncope.
- Diagnostic workup revealed a large pericardial cyst compressing the left ventricle.
- The patient underwent successful surgical resection of the pericardial cyst via cardiothoracic surgery.
Main Results:
- The patient experienced complete resolution of near-syncope following cyst resection.
- Hospital course was uneventful, with discharge seven days post-operation.
- No recurrence of syncopal episodes was noted at follow-up.
Conclusions:
- Pericardial cysts, though usually benign, can present with severe symptoms like outflow obstruction.
- Surgical resection is an effective treatment for symptomatic pericardial cysts causing hemodynamic compromise.
- While surveillance is an option for asymptomatic cases, symptomatic patients benefit from intervention.
Case Presentation:
A 41-year-old otherwise healthy male presented to the emergency department with recurrent exertional near-syncope. He was eventually found to have a large pericardial cyst causing an outflow obstruction. After resection of the cyst by cardiothoracic surgery, he had an uneventful hospital course and was discharged seven days later with no recurrent syncopal episodes.
Discussion:
We describe an otherwise healthy patient who exhibited symptomatic left ventricular outflow obstruction from a pericardial cyst. These cysts are usually benign and asymptomatic, although they can progress to cause significant morbidity or mortality. Surveillance is recommended if no hemodynamic compromise is present. Patients who are symptomatic or have hemodynamic compromise may undergo needle aspiration or thoracoscopy with resection.
More Related Videos
Related Concept Videos
Mitral Stenosis I: Introduction
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
Pericarditis II: Clinical Features and Diagnostic Tests
Heart Failure III: Clinical Manifestations
Mitral Regurgitation I: Introduction

