Why replication has more scientific value than original discovery

John P A Ioannidis1

  • 1Departments of Medicine,Health Research and Policy, and Biomedical Data Science,Stanford University School of Medicine,Stanford,CA 94305;Department of Statistics,Stanford University School of Humanities and Sciences,94305;Meta-Research Innovation Center at Stanford (METRICS),Stanford University,Stanford,CA 94305.jioannid@stanford.eduhttps://profiles.stanford.edu/john-ioannidis.

Summary

Original discovery is often overvalued compared to replication. A scientific model reveals that original discovery claims typically hold little value, emphasizing that replication is crucial for scientific worth.

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