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Summary
Malignant external otitis (MEO) is a severe ear infection that can lead to skull base osteomyelitis. Early diagnosis and treatment with debridement and antibiotics significantly reduce mortality from this condition.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Oncology
Background:
- Malignant external otitis (MEO) is a severe infection of the external ear canal.
- It can progress to osteomyelitis of the skull base if left untreated.
- The condition is more common in summer and in patients with diabetes.
Purpose of the Study:
- To analyze the clinical characteristics, risk factors, and outcomes of malignant external otitis (MEO).
- To evaluate the effectiveness of current treatment strategies for MEO.
Main Methods:
- Retrospective review of 50 patients diagnosed with malignant external otitis (MEO) between 1972 and 1985.
- Analysis of patient demographics, clinical presentation, comorbidities (especially diabetes), and treatment outcomes.
Main Results:
- All patients presented with severe earache and granulation tissue in the ear canal.
- Five patients experienced multiple cranial nerve involvement.
- Diabetes was present in 68% of patients.
- Mortality decreased as treatment protocols improved over time.
Conclusions:
- Malignant external otitis (MEO) requires prompt diagnosis and aggressive management.
- Treatment involves local debridement and a 6-8 week course of antibiotics, including semi-synthetic penicillin and an aminoglycoside.
- Improved treatment strategies have led to a reduced mortality rate.