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Updated: Jan 25, 2026

IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution
Chun Wu1, Ke-Jia Wu, Jin-Biao Liu
1Department of Chemistry, Hong Kong Baptist University, Kowloon, Hong Kong, China. edmondma@hkbu.edu.hk.
Abstract:
We have designed for the first time a dual-functional luminescent probe and inhibitor of neuraminidase (NA), a key influenza target. The lead iridium(iii) complex exhibited enhanced inhibition against NA compared to the FDA-approved antiviral drug, oseltamivir, and could detect NA even in the presence of an autofluorescent background.
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