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Vitreomacular Interface Abnormalities and Glaucoma in an Elderly Population (The MONTRACHET Study)
Julie Blanc1, Alassane Seydou2,3, Inès Ben Ghezala1
1University Hospital, Department of Ophthalmology, Dijon, France.
Investigative Ophthalmology & Visual Science
|May 9, 2019
Summary
Vitreomacular interface abnormalities (VMIA) prevalence was similar in elderly glaucoma and non-glaucoma patients. Macular OCT findings require careful interpretation for glaucoma management in older adults.
Area of Science:
- Ophthalmology
- Geriatric Medicine
- Retinal Imaging
Background:
- Vitreomacular interface abnormalities (VMIAs) are common in aging eyes.
- Glaucoma affects optic nerve health, and its impact on the macula is of interest.
- Understanding VMIA prevalence in elderly glaucoma patients is crucial for accurate diagnosis and management.
Purpose of the Study:
- To determine the prevalence of vitreomacular interface abnormalities (VMIAs) in a French elderly population with glaucoma.
- To compare VMIA prevalence between glaucomatous and non-glaucomatous individuals in this cohort.
Main Methods:
- Utilized data from the MONTRACHET population-based study (Dijon, 2009-2013).
- Included 1130 participants (2225 eyes) aged over 75 years.
- Analyzed prevalence of VMIAs, including vitreomacular adhesions, epiretinal membranes, and macular cysts.
Main Results:
- Overall VMIA prevalence was similar between glaucoma (51.85%) and non-glaucoma (53.92%) groups.
- Epiretinal membranes were more frequent in glaucoma patients (47.06% vs. 38.13%).
- Macular cysts were more frequent with preservative-free eye drops (26.67%) compared to preservative-containing ones (3.37%, 5.76%).
Conclusions:
- The prevalence of VMIAs is high in the elderly and comparable between glaucomatous and non-glaucomatous individuals.
- Macular optical coherence tomography (OCT) findings should be interpreted cautiously in elderly glaucoma patients.
- Further research may be needed to clarify the clinical significance of VMIA subtypes in glaucoma management.
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